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But it wasn't until the early 1950s that researchers demonstrated that the compound worked as well as the two popular pain relievers of the time — aspirin and acetanilide — with fewer side effects.

After further investigation, they realized they hadn’t even administered naphthalene at all, but rather a then-obscure drug called acetanilide, which the pharmacist had given them by mistake.

When heated with aniline it yields phenol and acetanilide.

Influence of certain drugs upon the toxicity of acetanilide and antipyrine.

Anilides, compounds in which the amino group is substituted by an acid radical, are prepared by heating aniline with certain acids; antifebrin or acetanilide is thus obtained from acetic acid and aniline.