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Researchers have shown, for example, that aminoglycoside antibiotics can cause deafness by damaging mitochondria in the hair cells of the ear3.

Benítez-Páez, A., Cárdenas-Brito, S., Corredor, M., Villarroya, M. & Armengod, M. E. Impairing methylations at ribosome RNA, a point mutation-dependent strategy for aminoglycoside resistance: the rsmG case.

Investigators focused on aminoglycoside antibiotics, which doctors rely on to treat meningitis, bacteremia, and respiratory infections in cystic fibrosis patients.

Healthy mice given a low amount of an aminoglycoside developed a small degree of hearing loss.

A fluorinated analogue of the naturally occurring aminoglycoside neomycin – well known as an over-the-counter ointment for minor skin abrasions – could lead to a range of much-needed antibiotics in the arms race against aminoglycoside resistant bacteria.