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He said because both benzodiazepines and nitazenes were depressants, “their combined effect increases the risk of overdose significantly”.

The report also confirms psychoactive substances such as benzodiazepines are posing significant dangers.

Nitazines, often mixed into heroin, are now being cut with benzodiazepines too.

Other Schedule IV drugs include the opioid tramadol and a group of depressants known as benzodiazepines.

These interactions can be particularly common with pain medications and sleep aids like benzodiazepines, sometimes causing over-sedation.