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A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, examined the relationship of the engagement of emotion regulation to real-world responses to stress in order to better understand stress-related increases in suicide risk in depression.

Editor-in-Chief of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Cameron S. Carter, MD, University of California Irvine, comments, "Flexibility in emotion regulation is generally understood to be a marker of psychological health. However, in the current study researchers found that reflexively engaging emotion regulation in the face of unexpected stressors may not be helpful or effective in all circumstances. These findings, which leverage functional imaging combined with real-world in the moment assessments, are important to further our understanding of how to effectively deal with stress in daily life."

The findings, appearing in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, help explain the so-called mystical experiences people report during the use of psychedelics and are pertinent to the psychotherapeutic applications of psychedelic drugs to treat psychiatric disorders such as depression.

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

Commenting on the findings, John Krystal, MD, Editor of Biological Psychiatry, says, "Arachidonic acid is typically a widely present omega-6 fatty acid in the body and brain that contributes to the health of cell membranes. This study provides a fascinating step forward in the effort to develop blood biomarkers of bipolar disorder risk, particularly in those patients with bipolar disorder and risk gene variations in the FADS1/2/3 gene cluster."