CRISPR Definition & Meaning

CRISPR

[ kris-per ]

Phonetic (Standard)IPA

noun

Biochemistry. a unique cluster of short, repeated DNA sequences found in bacterial genomes and capable of fighting viruses:
CRISPR enables bacteria to integrate foreign DNA into their genome.
Genetics. the technology of targeting a DNA-detecting molecule to a specific genetic sequence for the purpose of editing a gene’s base pairs:
The approach called CRISPR should speed up the process by allowing researchers to study the entire genome at once.

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51�Թ� History and Origins

Origin of CRISPR¹

First recorded in 2000–05; acronym from C(lustered) R(egularly) I(nterspaced) S(hort) P(alindromic) R(epeats)

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Example Sentences

Examples have not been reviewed.

In the laboratory, a gene-editing tool called Crispr is used.

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Crucially foetal haemoglobin is not affected by sickle cell disease, so Crispr acts by dampening down the "switch" that makes the body produce the adult form.

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It relies on the a tool called Crispr, which won the Nobel Prize for Chemistry in 2020.

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The introduction of the CRISPR/Cas9 method represented a methodological breakthrough for the researchers, as it enabled the establishment of the first transgenic migratory locusts expressing the genetically encoded calcium sensor GCaMP in olfactory sensory neurons.

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As reported in the Proceedings of the National Academy of Sciences, the researchers, using a technique known as CRISPR/Cas9 DNA editing that selectively modifies the DNA of living organisms, inserted the same genetic mutations found in humans with Tourette disorder into the corresponding genes in mouse embryos.

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