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The drugs that Janssen developed included a fentanyl patch and a tablet that was crush-resistant, marketed under names such as Duragesic and Nucynta, which, according to Johnson & Johnson, accounted for less than 1% of total opioid prescriptions in the United States.

The research, published in the journal Nature, could lead to "tough, impact- and crush-resistant materials", says a team led by David Kisailus of the University of California, Irvine.

Now scientists are studying what the bug’s crush-resistant shell could teach them about designing stronger planes and buildings.

Abuse of OxyContin continued until 2010 when Purdue introduced a crush-resistant formulation, the report said.

Five years ago, Houston entrepreneur Shan Shi saw an opportunity in China’s thirst for oil under the South China Sea and founded a company to learn how to make a type of crush-resistant foam that helps keep deepwater drilling rigs afloat.