51Թ

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View synonyms for

de novo

[ dee noh-voh, dey, dih; Latin de noh-woh ]

adverb

  1. anew; afresh; again; from the beginning:

    We reviewed the court’s decision de novo during the rehearing.

  2. independently of external forces; from within; spontaneously:

    Mutations associated with autism often occur de novo rather than through inheritance.



adjective

  1. occurring or arising spontaneously or independently of external forces; spontaneous: de novo synthesis of steroids from cholesterol.

    de novo mutations;

    de novo synthesis of steroids from cholesterol.

  2. made from scratch rather than developed from or based on something preexisting, and hence new, novel, or of a new type: de novo banks.

    de novo protein design;

    de novo banks.

  3. De No·vo, noting or related to a type of FDA classification allowing novel medical devices with no precedent on the market to be sold: De Novo classification.

    a De Novo request;

    De Novo classification.

de novo

/ diː ˈnəʊvəʊ /

adverb

  1. from the beginning; anew
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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51Թ History and Origins

Origin of de novo1

First recorded in 1620–30; from Latin dē novō “anew, afresh, again”

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