51�Թ�

When someone is taking an ACE inhibitor like benazepril, captopril, enalapril or lisinopril, extra potassium can become life-threatening.

ACE inhibitors such as enalapril or lisinopril help the body hang on to potassium.

A clinical trial showed it reduced the risk of death and hospitalization from heart failure versus another drug, enalapril.

In PARADIGM angioedema occurred in 19 Entresto patients and 10 enalapril patients. Entresto should not be used while patients are also taking an ACE inhibitor as this increases the risk of angioedema.

Most importantly, an analysis of dementia adverse events in the pivotal PARADIGM-HF trial finds no signal for any increase in the risk of dementia among patients who received Entresto compared to control patients receiving enalapril.