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The barren layer or ependyma of the cortex was in places twice as thick in this brain as in the brain of normal beings.

The lateral ventricle is lined by a ciliated epithelium called the ependyma.

This ependyma is the histologic factor of the enormous weight of macrocephalic brains.

In a macrocephalic case coming under the observation of Kiernan, of Chicago, in which the brain weighed 68 ounces, the ependyma was five times the normal thickness.