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Willem Overwijk, an associate professor in the department of melanoma medical oncology at MD Anderson Cancer Center, and his colleagues found that a mineral oil known as incomplete Freund’s adjuvant, or IFA, that is added to cancer vaccines to stimulate the immune system, may do too good a job.

Also, the researchers in the new study used an additive called complete Freund’s adjuvant to boost the immune reponse in the mice.