HOMOGENTISIC ACID Definition & Meaning

homogentisic acid

[ hoh-muh-jen-tis-ik, -tiz-, hoh- ]

Phonetic (Standard)IPA

noun

an intermediate compound in the metabolism of tyrosine and of phenylalanine, found in excess in the blood and urine of persons affected with alkaptonuria.

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51�Թ� History and Origins

Origin of homogentisic acid¹

First recorded in 1890–95; homo- + gentisic acid

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Example Sentences

Examples have not been reviewed.

Mice that have been genetically modified to develop hereditary tyrosinemia, a human liver disease, will resist the disease if they also lose another gene on chromosome 16 called homogentisic acid dioxygenase.

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