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One would think the viruses and bacteria that have tormented humanity since time immemorial would never find a friend in the species — human beings — they so routinely sicken and kill.

But the film, which hit theaters this Friday, is an attempt to upend many of the narrative tropes that have defined stories about disfigured and disabled people since time immemorial.

“We follow the Santa Ana river, so this goes back to time immemorial that we’ve been aware of this sacred ceremonial space.”

“This is a down payment on the state’s commitment to do better by the Native American communities who have called this land home since time immemorial,” Newsom said in a statement.

So being allowed to live on federally designated land — in a region where they had been nature’s proud stewards since time immemorial — represented a bittersweet milestone.