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"Highlighting relevant incidents in relation to the charges may make it seem like I am being portrayed negatively towards my children. But I love my children immensely."

George Weston, chief executive of ABF, said: "I am immensely disappointed. Colleagues and others must be treated with respect and dignity. Our culture has to be, and is, bigger than any one individual."

Brown said the family was "immensely proud of all Christina achieved".

But Prof Isaacs, who has dedicated his career to the condition, said it would make him and his team immensely proud to have developed the treatment.

Pasta Arrabbiata is an immensely popular dish for a reason, so if heat is your game, then feel free to make your sauce a super hot one.