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After fertilization the nucleus of the egg divides, the first stages of karyokinesis being apparent even before complete fusion of the male and female nuclei has occurred.

The facts of karyokinesis are generally claimed by the school of Weismann as making exclusively in favour of continuity as absolute.

The similarity of these processes among all living creatures, vegetable and animal, and their extreme complication, suggests that karyokinesis is the chief factor in distributing the hereditary mass to the growing organism.

Nuclear division is usually accompanied by all the essential features of karyokinesis.

This phenomenon, namely the production of karyokinesis from centres of catabolism, may account for the abnormal karyokinesis of cancer cells and the like.