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DNA m is a natural process where small chemical groups, called methyl groups, are added to certain parts of our DNA.

This is why RNA-methylation needs to be tightly controlled, taken care of by a set of proteins: "writers" deposit, "readers" recognize and "erasers" remove the methyl group.

This modification is enabled by the transfer of methyl groups to nucleobases at certain positions in the DNA.

In particular, they focused on a process known as DNA methylation, in which molecules called methyl groups are added to different genes, often changing the way they are expressed.

DNA methylation, which involves methyl groups attaching to nucleotides in DNA, varies with age, and these epigenetic clocks use certain variations in methylation to estimate biological age.