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While the blobfish is known for its misshapen silhouette, in its natural deep-sea habitat it actually resembles a regular fish, with its shape kept together by the high water pressure.

Sickle cell disease can be life-threatening and cause recurring intense pain, when blood vessels become blocked by misshapen red cells.

What has followed is a generation of pitchers with better stuff across the board, but also more red flags for potential long-term injuries — from worn-down elbow ligaments to misshapen bones in their shoulder.

So-called "ugly" produce — misshapen food that never makes it to the grocery store because of its looks — falls into this category.

These misshapen proteins can disrupt mitochondria’s ability to produce the energy cells need.