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The reason became clear: Microbes were feasting on Assi’s necrotic flesh.

"He's in excruciating agony because his hip bones are now no longer ball or socket, just jagged, worn, necrotic bones on bones. There are cysts in the joints where cartilage once lived," Mrs Speirs said.

Second, the scientists found that placing RvE1 on exposed and severely infected and necrotic pulp did not facilitate regeneration.

The drug supply is getting steadily more unpredictable, as more substances are found to contain fentanyl and animal tranquilizers like xylazine that can generate horrific necrotic injuries.

Conveniently, Ernest’s personality has been wiped by a case of necrotic amnesia that allows this Greatest Generation ghost to pal around with today’s teenagers.