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Even common pain medications like nonsteroidal anti-inflammatory drugs, such as ibuprofen, cause tens of thousands of hospitalizations and thousands of deaths each year from gastrointestinal damage.

PUD can also develop from taking certain medications, specifically the class of pain relievers known as NSAIDS, or nonsteroidal anti-inflammatory drugs.

It can also be caused by excessive use of nonsteroidal anti-inflammatory drugs such as ibuprofen, naproxen and high-dose aspirin.

High on the list are nonsteroidal anti-inflammatory drugs such as ibuprofen.

Managing pain with steroids and nonsteroidal anti-inflammatory drugs, like ibuprofen, can actually turn a wrenched back into a chronic condition, the study found.