51�Թ�

The Inspiration4 crew members consented to participating in medical experiments — collecting samples of blood, urine, feces and saliva during their flight — and to allowing the data to be cataloged in an online archive known as the Space Omics and Medical Atlas, or SOMA, which is publicly available.

Top disease-associated genes and pathways across regions, omics, and/or traits implicated biological processes in both neuronal and non-neuronal cells.

The authors also caution that they did not fully characterize all cell-subtypes and cell states, and that future studies are required to understand contrasting molecular signals across omics or brain regions.

The researchers combined eight cutting-edge omics technologies, including single-cell RNA sequencing, whole-genome sequencing, and spatial transcriptomics to map and localise genes expressed in the tissue.

"PERCEPTION allows for the use of rich information within single-cell omics to understand the clonal architecture of the tumor and monitor the emergence of resistance."