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It is most often used to study how macromolecules, cellular organelles, or cells are spatially organized, providing structural and contextual insights at sub-nanometer resolution.

The ion channel controls the breakdown of important proteins in endolysosomes -- cell organelles that are involved in transport and degradation processes -- and thus influences signaling pathways that regulate tumor growth.

It's a core function, but little studied in the setting of cancer immunology, especially when compared to other organelles like the mitochondria or endoplasmic reticulum.

It would mark the first time synthetic vaults have been injected into humans, and perhaps the beginning of a new turn in the spotlight for these mysterious organelles.

In addition, reduced ergosterol levels also trigger a second "self-destruct" pathway, which causes the cell to "self-eat" its own nuclei and other vital organelles -- a process known as macroautophagy.