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Most flu vaccines contain a small amount of egg proteins, such as ovalbumin.

The researchers showed that the ovalbumin disperses throughout the cytoplasm of cells in both culture and tumors.

To find out, he and colleagues gave the mice ovalbumin—the main protein found in egg whites and a known trigger of anaphylaxis—and used electrodes and microscopy to record and measure neuron activity.

As eggs are scrambled over heat, their proteins — mainly ovalbumin and ovotransferrin — begin to denature and become entangled, forming a spongy matrix that traps moisture.

To track the activation of CD4 T cells, the authors took CD4 T cells engineered to express a TCR that recognizes the ovalbumin antigen, and transferred them into tumour-bearing mice.