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Invasive species such as the overbite clam consumed the zooplankton on which juvenile smelt had fed, toxic chemicals in farm runoff fouled the waters.

The estuary already has a long list of non-native species, including bass, water hyacinth, Asian clams and overbite clams.

Comedy nerds and oddballs of all stripes embraced the show, especially its singularly off-putting heroine, a woman with a garish overbite, a sordid past and a strangely infectious nasal drawl.

Could anything be done about his overbite, he asked?

Humans’ teeth, which once met in a predator’s vise, slid into an overbite as people turned to the softer foods that agriculture provided, shaping sounds such as “farm,” “vivid,” “fulvous” and “favorite.”