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The numberings of nearby amino acid residues, which are shown along with these cofactors, are listed below each cofactor. b, Fitting of different secondary structure elements to cryo-EM density. c, Eleven identified lipids are modelled as phosphatidylethanolamine molecules. d, The triacylated cysteine at the N terminus of ActE shown along with 15 downstream amino acids.

This is achieved, at least in part, through reduction of the levels of mitochondrial phosphatidylserine decarboxylase, which is involved in the synthesis of mitochondrial phosphatidylethanolamine.