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The first is a phototoxic reaction, often seen with certain antibiotics such as tetracycline.

The pathology would help him distinguish the inflammation of hives from the more destructive phototoxic reaction, which destroys the skin cells.

The plant's sap contains a chemical called furocoumarins, and when it mixes with sunlight, it causes a phototoxic reaction on skin called phytophotodermatitis.

“Those can definitely be phototoxic, especially the retinoids,” says Rech.

“Phototoxic effects are going to appear like a really bad sunburn.”