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Truvada is used in treating HIV and as a preexposure prophylaxis for people at high risk, including those with multiple sexual partners and those who share needles while injecting drugs.

That work has included ramping up HIV testing and PrEP, or preexposure prophylaxis, programs, as well as expanding care for transgender people living with the virus.

District Judge Reed O’Connor builds on a September judgment in which he also said the ACA requirement that employers cover preexposure prophylaxis treatment to prevent HIV violates the Religious Freedom Restoration Act.

“Preexposure prophylaxis is something we don’t have a replacement for,” Glatt says.

In a 2008 monkey study led by Moss, published in the Proceedings of the National Academy of Sciences, researchers compared preexposure vaccination against monkeypox from a single dose of MVA and one dose of a cruder version of ACAM2000 called Dryvax.