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The researchers found that people with slower pupillary constriction had significantly greater improvement in depression after 10 sessions if they received iTBS rather than 10 Hz treatment.

The final step is a neurological evaluation featuring a cervical spine exam, including range of motion/pain, evaluation of speech, observation of gait, eye movements and pupillary exam.

It would be developed with touchscreen technology so that providers can access an immediate database on pupillary light reflex responses.

However, “there are much more striking effects” that could have been used to demonstrate the pupillary response.

The new work builds on an earlier study by Wheatley and psychologist Olivia Kang, now at Harvard University, who showed that pupillary synchrony serves as a measure of shared attention.