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The 60 patients in the study presented at their GPs or to A&E with a range of symptoms including shortness of breath, muscle pain, rashes, and reduced blood flow to the fingers, known as Raynaud's disease.

Her primary care doctor sent her to a rheumatologist who diagnosed Raynaud’s disease, a typically self-limiting condition in which small arteries that supply blood to the skin overreact to stress or cold temperatures.

Anastasia is finding some relief for the migraines but not much for the feet issues, which have also resulted in a diagnosis of Raynaud's disease.

FM also presents with sleep disorders, irritable bowel syndrome, cognitive disturbances and memory loss, Raynaud’s disease, muscle tightness and stiffness, hormonal dysfunction, anxiety and depression and much more.

Sufferers of cold urticaria disorder get an itchy allergic reaction to cold air, and Raynaud’s disease causes fingers and toes to go numb at times like these.