51Թ

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sickle cell trait

noun

Pathology.
  1. the usually asymptomatic hereditary condition that occurs when a person inherits from only one parent the abnormal hemoglobin gene characteristic of sickle cell anemia.


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51Թ History and Origins

Origin of sickle cell trait1

First recorded in 1925–30
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Example Sentences

Examples have not been reviewed.

Scientist Errol Morrison and author Patrick Cooper's controversial hypothesis, published in the West Indian Medical Journal,, external was that the prevalence of sickle cell trait - a mutation that causes round, red, oxygen-carrying blood cells to curl up in a sickle shape - among people of West African origin had "triggered a series of physiological adjustments, which, incidentally, had favourable athletic consequences".

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The disease, which can stunt physical growth, is more common in malaria-prone regions, notably Africa and India, because carrying the sickle cell trait helps protect against severe malaria.

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Even a common test used to manage diabetes can underestimate blood sugar levels for patients who have sickle cell trait, which is present in nearly 1 in 10 African Americans.

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It’s more common in malaria-prone regions because carrying the sickle cell trait helps protect against severe malaria.

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Scientists believe being a carrier of the sickle cell trait helps protect against severe malaria, so the disease occurs more often in mosquito-prone regions such as Africa or in people whose ancestors lived in those places.

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