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England prop Mackenzie Carson has been ruled out of the rest of their Women's Six Nations campaign with an ankle injury.

After featuring late off the bench against Italy in York, a first start in this year's Women's Six Nations came in the 67-12 hammering of Wales at Principality Stadium.

But after the first 10 minutes England showed their class, scoring through every facet of play as they remain on course for a seventh consecutive Six Nations title and a fourth consecutive Grand Slam.

France produced a clinical second-half performance in La Rochelle to inflict a first defeat of this year's Women's Six Nations on Scotland.

Mitchell has made 13 changes to his starting XV, with a large majority of his side who played key roles in last year's Six Nations and WXV1 title successes returning.