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These dephosphorylation enzymes consist of a catalytic subunit responsible for dephosphorylation activity and a regulatory subunit controlling the enzyme's subcellular localization and enzyme activity.

Soft X-rays are able to provide chemical information about samples and detailed images at the subcellular level, but their use has been limited due to the very specialized equipment required and, in biology, the damage they cause to living cells.

But the scientists wanted to make sure that the CB5D protein from an ancient species, like liverwort, was expressed in the same subcellular structures as modern CB5D.

The group found that a subcellular structure called actomyosin drives much of the development process, especially the lower wing disc flattening.

"The quality of preservation of the fossil frog skin is amazing -- even subcellular structures, such as collagen fibres, are preserved." said study lead, PhD researcher Daniel Falk.