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PKA consists of a catalytic subunit responsible for kinase activity and a regulatory subunit that inhibits enzyme activity.

Human neurogenesis is not fully understood, but certain mutations within subunits of a protein complex called Integrator -- which influences neurogenesis -- have been associated with neurodevelopmental disorders.

One particular SPT subunit stood out to the researchers as the subject of future research, since the team suspects it is responsible for selectively spitting dangerous lipids out of the liver.

"We already knew that certain mutations in these subunits are linked to the eye disease retinitis pigmentosa," says Dr. Cristian Prieto-Garcia from the Institute of Biochemistry II, the first author of the study.

But cells containing an addition to their catalytic subunit generate the kinase in excessive amounts -- which is the real culprit.