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Charlene said she was on the "highest levels" of fentanyl, tramadol, ketamine and took between 20 and 30 pills every day in her recovery.

Aveo's new product is even more dangerous than the tramadol it has replaced.

Unlike tramadol, which is legal for use in limited doses, the tapentadol-carisoprodol cocktail "does not sound like a rational combination", he said.

The government banned the sale of tramadol without prescription, imposed strict limits on the maximum dose, and cracked down on imports of illegal pills.

At the same time, Indian authorities tightened export regulations on tramadol.