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Still, those relationships were tested and strained repeatedly, and in recalling those tribulations, Hoppus has tried to be empathetic with all involved.

Fielding says she finds it "comforting" that women in their 20s have a real interest in Bridget’s trials and tribulations.

But who better to navigate the trials and tribulations of the holiday season than your best friend?

Ph.D., and colleagues write in the review, "Trials and tribulations of cell therapy for heart failure: an update on ongoing trials," published in Nature Reviews Cardiology.

"When you haven't lived life, to go through trials and tribulations whilst being under the spotlight is a very difficult thing. And who is there to support?"