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What's more, patients whose leukemia cells more closely reflected young blood cell production had a much worse prognosis than those whose leukemia cells more closely reflected old blood cell production.

Further investigation identified seven transcription factor genes that strongly influence whether leukemia cells looked like old or young blood cells.

Future studies are planned to test whether the disease takes advantage of the highly proliferative capacity of young blood cells to make patients' leukemia more deadly than older, less vigorous blood cells.

"If we can develop drugs that target key factors that drive young blood cell production, maybe the leukemia will just reflect old blood cell production and be easier to treat," said Hojun Li, M.D.,

Paley went on to make records there with John Wesley Harding and the Mighty Lemon Drops before helming a would-be comeback album by Lewis called “Young Blood” in 1995.