ADENYLATE CYCLASE Definition & Meaning

adenylate cyclase

[ uh-den-l-it, -eyt, ad-n-l- ]

Phonetic (Standard)IPA

noun

Biochemistry.

an enzyme that catalyzes the conversion of ATP to cyclic AMP.

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51�Թ� History and Origins

Origin of adenylate cyclase¹

First recorded in 1965–70; aden(ine) + -yl + -ate ²

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Example Sentences

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Manejwala, F., Kaji, E. & Schultz, R. M. Development of activatable adenylate cyclase in the preimplantation mouse embryo and a role for cyclic AMP in blastocoel formation.

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Through rational drug design and chemical screening, we have identified a lead candidate AC1 inhibitor, NB001, which is relatively selective for AC1 over other adenylate cyclase isoforms.

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